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Blog Archive


The Report: Part 4

June 2016

With this post, we will change the focus just a little, to discuss surgical deliveries and their effects on fetal and maternal oxytocin.  Once again, I'd highly recommend accessing this report and saving it, as it is chock full of excellent information to which you'll refer time and again.

Lire la suite : The Report: Part 4

The Report, Part 3

May 2016

In over 30 pages of oxytocin physiology, the Buckley report gives details of the powers of this wondrous hormone. I want to highlight two things which I continue to find awe-inspiring.

Buckley states, "Oxytocin mechanisms may help to protect the fetal brain from labor hypoxia, according to animal studies. This mechanism involves the transfer of maternal oxytocin through the placenta and into the fetal brain, and may be inactive before the physiologic onset of labor. High-dose synthetic oxytocin and oxytocin-antagonist drugs (used in women to treat threatened premature labor) inactivate this neuoprotection in animal studies. Deficits in this neuroprotection are associated with animal models of autism," (2015, p 39). As oxytocin crosses the blood-brain barrier into the fetal brain, brain activity is reduced through activity of the neurotransmitter gamma-aminobutric acid (GABA). This begins 24 hours just prior to the physiologic onset of labor, creating a protection for the infant again birth hypoxia. With the administration of high levels of synthetic oxytocin, these neuroprotective effects are reduced.

Lire la suite : The Report, Part 3

The Report, Part 2

May 2016

"The outcomes of maternity care and maternity care interventions have traditionally focused on important short-term outcomes such as perinatal mortality, newborn morbidity (e.g., measured by Apgar score, cord blood analysis, and/or admission to advanced care), and certain maternal outcomes. There is increasing recognition, including from other frameworks, that exposures during the highly sensitive perinatal period may have implications for longer-term health and well-being" (Buckley, 2015).

Let's take a look at the a few of the other frameworks mentioned in the report by Buckley, and why they should be taken into consideration when looking at the hormonal physiology of labor and delivery.

Lire la suite : The Report, Part 2

The Report, Part 1

May 2016

In my last post, I began the discussion of a recent report by Sarah J. Buckley, entitled, "Hormonal Physiology of Childbearing: Evidence and Implications for Women, Babies, and Maternity Care", (2015). Throughout the month of May, I will present various pieces of information from this commissioned report, through Childbirth Connection, that was published in January of last year.

In Part 1, let's look at the physiologic onset of term labor in humans.

Lire la suite : The Report, Part 1

Care of the Mother/Baby Dyad

April 2016

For the next several weeks, I will be sharing information from a 2015 study released through Childbirth Connection, entitled, "Hormonal Physiology of Childbearing: Evidence and Implications for Women, Babies, and Maternity Care.”  In this commissioned report, the author takes researched evidence to view four hormonal systems involved in childbearing: oxytocin, beta-endorphin, epinephrine-norepinephrine and cortisol (the stress system), and prolactin.  This is some powerful information and may bring on a great deal of thought and discussion about our routine practices around the care of pregnant, birthing, and postpartum women.

Lire la suite : Care of the Mother/Baby Dyad

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